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PCSK9-IN-1

Names

[ CAS No. ]:
2730022-10-1

[ Name ]:
PCSK9-IN-1

Biological Activity

[Description]:

PCSK9-IN-1 is a novel and highly potent cyclic peptide PCSK9 inhibitor with a Ki value of 1.46 nM.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease

Research Areas >> Cardiovascular Disease

[References]

[1]. Alleyne C, et al. Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design. J Med Chem. 2020 Nov 25;63(22):13796-13824.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₅H₈₀FN₁₁O₁₂S₂

[ Molecular Weight ]:
1290.53

Related Compounds