5,7-Dihydroxycoumarin

Names

[ Name ]:
5,7-Dihydroxycoumarin

[Synonym ]:
5,7-Dihydroxy-cumarin
Coumarin derivative,1a
5,7-dihydroxy-chromen-2-one
2H-1-Benzopyran-2-one, 5,7-dihydroxy-
5,7-Dihydroxy-2H-chromen-2-one
5,7-dihydroxyocoumarin
5,7-DIHYDROXYCOUMARIN

Biological Activity

[Description]:

5,7-Dihydroxycoumarin is a coumarin isolated from the inflorescences of Macaranga triloba. 5,7-Dihydroxycoumarin has antibacterial activities[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Ishak Zakaria, et al. Flavonoids with antiplasmodial and cytotoxic activities of Macaranga triloba. Fitoterapia. 2012 Jul;83(5):968-72.

[2]. Yi-Ping Chin, et al. Synthesis and evaluation of antibacterial activities of 5,7-dihydroxycoumarin derivatives. Arch Pharm (Weinheim). 2011 Jun;344(6):386-93.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
506.4±19.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₆O₄

[ Molecular Weight ]:
178.141

[ Flash Point ]:
216.9±15.0 °C

[ Exact Mass ]:
178.026611

[ PSA ]:
70.67000

[ LogP ]:
0.86

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.689

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%