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MS 245 oxalate

Names

[ CAS No. ]:
275363-58-1

[ Name ]:
MS 245 oxalate

[Synonym ]:
MFCD19690952
1H-Indole-3-ethanamine, 5-methoxy-N,N-dimethyl-1-(phenylsulfonyl)-, ethanedioate (1:1)
MS 245 (oxalate)
2-[5-Methoxy-1-(phenylsulfonyl)-1H-indol-3-yl]-N,N-dimethylethanamine ethanedioate (1:1)

Biological Activity

[Description]:

MS 245 oxalate is a potent antagonist of 5-HT6 receptor with a Ki of 2 nM[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Abate C, et al. Interaction of chiral MS-245 analogs at h5-HT6 receptors. Bioorg Med Chem Lett. 2005;15(15):3510-3513.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H24N2O7S

Related Compounds