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SOS1-IN-7

Names

[ CAS No. ]:
2755415-30-4

[ Name ]:
SOS1-IN-7

Biological Activity

[Description]:

SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC50s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

SOS1-G12D:20 nM (IC50)

SOS1-G12V:67 nM (IC50)

[References]

[1]. Pyridine-pyrimidine derivative, preparation method therefor and pharmaceutical use thereof. WO2021249519A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₅F₃N₄O₃

[ Molecular Weight ]:
462.46

Related Compounds