Anticancer agent 39

Names

[ Name ]:
Anticancer agent 39

Biological Activity

[Description]:

Anticancer agent 39 (compound B12), a fluorescent derivative of Jiyuan Oridonin A (JOA), induces the collapse of mitochondrial membrane potential (MMP)and thus induced apoptosis.Anticancer agent 39 inhibits cell cloning and migration.Anticancer agent 39 exhibits promising anti-proliferative activity against HGC-27 cells with IC50 value of 0.39 μM[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Chen Zhou, et al. Synthesis, biological evaluation and cellular localization study of fluorescent derivatives of Jiyuan Oridonin A. Eur J Med Chem. 2022 Feb 5;229:114048.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₀H₆₅N₅O₁₀

[ Molecular Weight ]:
896.08

Anticancer agent 39

Names

Biological Activity

Chemical & Physical Properties

Related Compounds