PRMT5-IN-27

Names

[ CAS No. ]:
2790567-82-5

[ Name ]:
PRMT5-IN-27

Biological Activity

[Description]:

PRMT5-IN-27 (compound 481) is an inhibitor of PRMT5. PRMT5-IN-27 inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[References]

[1]. Shon Booker, et al. Prmts inhibitors. WO2022132914A1. 2022-06-23.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H19F3N4O3

[ Molecular Weight ]:
444.41

Related Compounds