4-[(2H3)Methyloxy]benzoic acid

Names

[ Name ]:
4-[(2H3)Methyloxy]benzoic acid

[Synonym ]:
Benzoic acid, 4-(methyl-d-oxy)-
4-trideuteriomethoxy-benzoic acid
p-methoxy-d3-benzoic acid
4-[(H)Methyloxy]benzoic acid

Biological Activity

[Description]:

4-Methoxy-benzoic acid-d3 is the deuterium labeled 4-Methoxy-benzoic acid[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
278.3±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₅D₃O₃

[ Molecular Weight ]:
155.166

[ Flash Point ]:
115.5±13.3 °C

[ Exact Mass ]:
155.066177

[ PSA ]:
46.53000

[ LogP ]:
1.96

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.546

[ Storage condition ]:
2-8°C

4-[(2H3)Methyloxy]benzoic acid

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds