1-Naphthalenealanine

Names

[ Name ]:
1-Naphthalenealanine

[Synonym ]:
L66J B1YZVQ
2-amino-3-naphthalen-1-ylpropanoic acid
1-naphthalanine
3-(1-Naphthyl)-DL-alanine
3-(1-Naphthyl)alanine
D,L-β-(1-Naphthyl)alanine
1-Naphthalenealanine
D,L-1-naphthylalanine
2-Amino-3-(1-naphthyl)propanoic acid
1-Naphthalenepropanoic acid, α-amino-
2-amino-3-(naphthalen-1-yl)propanoic acid (non-preferred name)
MFCD00067507
2-Amino-3-(1-naphthalenyl)propanoic acid

Biological Activity

[Description]:

2-Amino-3-(naphthalen-1-yl)propanoic acid is an alanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1077.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
412.3±33.0 °C at 760 mmHg

[ Melting Point ]:
239℃

[ Molecular Formula ]:
C₁₃H₁₃NO₂

[ Molecular Weight ]:
215.248

[ Flash Point ]:
203.2±25.4 °C

[ Exact Mass ]:
215.094635

[ PSA ]:
63.32000

[ LogP ]:
2.34

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.660

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis and characterization of more potent analogues of hirudin fragment 1-47 containing non-natural amino acids.

Biochemistry 37(39) , 13507-15, (1998)

Hirudin is the most potent and specific inhibitor of thrombin, a key enzyme in the coagulation process existing in equilibrium between its procoagulant (fast) and anticoagulant (slow) form. In a previ...

The A14 position of insulin tolerates considerable structural alterations with modest effects on the biological behavior of the hormone.

J. Protein Chem. 11(5) , 571-7, (1992)

As part of our aim to investigate the contribution of the tyrosine residue found in the 14 position of the A-chain to the biological activity of insulin, we have synthesized six insulin analogues in w...

Adding L-3-(2-Naphthyl)alanine to the genetic code of E. coli.

J. Am. Chem. Soc. 124 , 1836-1837, (2002)

An unnatural amino acid, L-3-(2-naphthyl)alanine, has been site-specifically incorporated into proteins in Escherichia coli. An orthogonal aminoacyl-tRNA synthetase was evolved that uniquely aminoacyl...