1-Tetradecanol-d29

Names

[ CAS No. ]:
284474-78-8

[ Name ]:
1-Tetradecanol-d29

[Synonym ]:
1-Tetradecan-d29-ol

Biological Activity

[Description]:

1-Tetradecanol-d29 is the deuterium labeled 1-Tetradecanol[1]. 1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity[2].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. XiaoyeGeng, et al. Design and fabrication of reversible thermochromic microencapsulated phase change materials for thermal energy storage and its antibacterial activity. Energy. Volume 159, 15 September 2018, Pages 857-869.

Chemical & Physical Properties

[ Melting Point ]:
38-40ºC(lit.)

[ Molecular Formula ]:
C14HD29O

[ Molecular Weight ]:
243.56600

[ Flash Point ]:
148ºC

[ Exact Mass ]:
243.41200

[ PSA ]:
20.23000

[ LogP ]:
4.67980

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H412

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
38

[ Safety Phrases ]:
37

[ RIDADR ]:
NONH for all modes of transport

Related Compounds