5-Hydroxy-6,7-dimethoxy-2H-chromen-2-one

Names

[ Name ]:
5-Hydroxy-6,7-dimethoxy-2H-chromen-2-one

[Synonym ]:
5-Hydroxy-6,7-dimethoxy-3,4-dihydro-2H-naphthalin-1-on
5-Hydroxy-6,7-dimethoxy-1-tetralon
5-hydroxy-6,7-dimethoxy-1-tetralone
5-hydroxy-6,7-dimethoxy-chromen-2-one
5-hydroxy-6,7-dimethoxycoumarin
5-Hydroxy-6,7-dimethoxy-2H-chromen-2-one
2H-1-Benzopyran-2-one, 5-hydroxy-6,7-dimethoxy-

Biological Activity

[Description]:

Tomentin is a compound isolated from Sphaeralcea angustifolia. Tomentin inhibits the formation of λ-carrageenan footpad edema at 58 %. Tomentin inhibits the phorbol ester-induced auricular edema formation by 57 %[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Pérez-Hernández J, et al. Sphaeralcic acid and tomentin, anti-inflammatory compounds produced in cell suspension cultures of Sphaeralcea angustifolia. Planta Med. 2014;80(2-3):209-214.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
421.9±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₀O₅

[ Molecular Weight ]:
222.194

[ Flash Point ]:
170.0±22.2 °C

[ Exact Mass ]:
222.052826

[ PSA ]:
68.90000

[ LogP ]:
0.77

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.588

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2932209090

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%