Pomalidomide-5-C8-NH2 hydrochloride

Names

[ CAS No. ]:
2863635-03-2

[ Name ]:
Pomalidomide-5-C8-NH2 hydrochloride

Biological Activity

[Description]:

Pomalidomide-5-C8-NH2 hydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-C8-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[References]

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H29ClN4O4

[ Molecular Weight ]:
436.93

Related Compounds