(S,R,S)-AHPC-C2-PEG3-BCN

Names

[ CAS No. ]:
2876198-36-4

[ Name ]:
(S,R,S)-AHPC-C2-PEG3-BCN

Biological Activity

[Description]:

(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL ligand, and can be used for synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[References]

[1]. Wang Z, et al. Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2. J Am Chem Soc. 2023 Oct 11;145(40):21871-21878.  

Chemical & Physical Properties

[ Molecular Formula ]:
C42H59N5O9S

[ Molecular Weight ]:
810.01

Related Compounds