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TKB245

Names

[ CAS No. ]:
2892688-16-1

[ Name ]:
TKB245

Biological Activity

[Description]:

TKB245 is a highly potent SARS-CoV-2 Mpro inhibitor that effectively blocks SARS-CoV-2 replication in VeroE6 cells[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Kohei Tsuji, et al. Structure-Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2-carbonyl Moieties. J Med Chem. 2023 Oct 12;66(19):13516-13529.  

Chemical & Physical Properties

[ Molecular Formula ]:
C30H35F4N5O5S

[ Molecular Weight ]:
653.69

Related Compounds