(9β,10α)-2β,16α-Dihydroxy-4,4,9,14-tetramethyl-19-norpregna-5-ene-3,11,20-trione

Names

[ Name ]:
(9β,10α)-2β,16α-Dihydroxy-4,4,9,14-tetramethyl-19-norpregna-5-ene-3,11,20-trione

[Synonym ]:
(2S,8S,9R,10R,13R,14S)-17-Acetyl-2,16-dihydroxy-4,4,9,13,14-pentamethyl-1,4,7,8,9,10,12,13,14,15,16,17-dodecahydro-2H-cyclopenta[a]phenanthrene-3,11-dione

Biological Activity

[Description]:

Hexanorcucurbitacin D is a cucurbitacin. Hexanorcucurbitacin D can be isolated from Trichosanthes cucumeroides roots. Hexanorcucurbitacin D can be used for the research of cardiovascular disease (CVD)[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Xianjing Zhang, et al. Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives. J Nat Prod. 2020 Dec 24;83(12):3536-3544.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₃₄O₅

[ Molecular Weight ]:
402.52400

[ Exact Mass ]:
402.24100

[ PSA ]:
91.67000

[ LogP ]:
2.87030