PHD-IN-2

Names

[ CAS No. ]:
2924182-42-1

[ Name ]:
PHD-IN-2

Biological Activity

[Description]:

PHD-IN-2 (Compound 91) is a PHD antagonist (IC50: < 5 nM). PHD-IN-2 induces erythropoietin synthesis in HEP3B cells (EC50: <2.5 μM). PHD-IN-2 can be used for research of cardiovascular disorders, metabolic disorders, hematological disorders, pulmonary disorders, kidney disorders, liver disorders, wound healing disorders, and cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase

[References]

[1]. Xiao DING, et al. Prolyl hydroxylase domain-containing protein (phd) inhibitors and uses thereof. Patent. US20230192723A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H27N7O4

[ Molecular Weight ]:
501.54

Related Compounds