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h-NTPDase-IN-2

Names

[ CAS No. ]:
2939933-03-4

[ Name ]:
h-NTPDase-IN-2

Biological Activity

[Description]:

h-NTPDase-IN-2 (compound 3l) is a pan-inhibitor of h-NTPDase, with IC50s of 0.35 μM (h-NTPDase1), 4.81 μM (h-NTPDase2), 37.73 μM (h-NTPDase3), 10.32 μM (h-NTPDase8), respectively[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
Research Areas >> Others

[Target]

IC50: 0.35 μM (h-NTPDase1), 4.81 μM (h-NTPDase2), 37.73 μM (h-NTPDase3), 10.32 μM (h-NTPDase8)[1]


[References]

[1]. Zaman G, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165. .

Chemical & Physical Properties

[ Molecular Formula ]:
C19H16N4S

[ Molecular Weight ]:
332.42

Related Compounds