Phenazine methylsulfate

Names

[ CAS No. ]:
299-11-6

[ Name ]:
Phenazine methylsulfate

[Synonym ]:
EINECS 206-072-1
5-methylphenylazinium methyl sulfate
PHENAZINE METHOLSULPHATE
Phenazine Methyl Sulfate
N-methyl phenazinium methylsulphate
Phenazine Methoshlphate
PMS,phenazine methosulfate
Phenazinium, 5-methyl-, methyl sulfate
5-methylphenazinium methylsulfate
5-Methylphenazinium methosulfate
PHENAZINE METHOSULFATE
5-Methylphenazin-5-ium methyl sulfate
PMS
MFCD00011923
PhenazineMethosulphate~
Phenazine methosulfa
5-Methyl-phenazinium
N-methylphenazinium methyl sulfate

Biological Activity

[Description]:

Phenazine methylsulfate is a free radical generator. Phenazine methylsulfate has been used as an electron transfer reactant in cell viability assays. Phenazine methylsulfate induces ssDNA break formation in the presence of the reducing agent NADPH. Phenazine methylsulfate induces oxidative DNA damage in an alkaline comet assay and apoptosis.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Signaling Pathways >> Anti-infection >> Bacterial

Chemical & Physical Properties

[ Melting Point ]:
158-160 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₄H₁₄N₂O₄S

[ Molecular Weight ]:
306.337

[ Exact Mass ]:
306.067413

[ PSA ]:
91.58000

[ LogP ]:
2.38630

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG1645000

CHEMICAL NAME :: Phenazinium, 5-methyl-, methylsulfate

CAS REGISTRY NUMBER :: 299-11-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H11-N2.C-H3-O4-S

MOLECULAR WEIGHT :: 306.36

WISWESSER LINE NOTATION :: T C666 BK INJ B1 &WSO&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 19 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Fish - salmon Sperm

DOSE/DURATION :: 3300 nmol/L

REFERENCE :: BICHAW Biochemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1962- Volume(issue)/page/year: 8,1238,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3658 No. of Facilities: 194 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 2761 (estimated) No. of Female Employees: 2298 (estimated)

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R36/37/38;R68

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
SG1645000

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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