Hydrocarbon chain derivative 1

Hydrocarbon chain derivative 1 is an active compound, with inhibitory activities against lipid synthesis.

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

Hydrocarbon chain derivative 1 is well tolerated with mild liver effects at 2000 mg/kg in rats[1]. Hydrocarbon chain derivative 1 shows inhibitory effect on lipid synthesis, with an IC50 of 11 μM[2].

[1]. Oniciu DC, et al. Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids. J Med Chem. 2006 Jan 12;49(1):334-48.

[2]. Oniciu DC, et al. Long hydrocarbon chain diols and diacids with central ether or ketone moieties that favorably alter lipid disorders. Pharmazie. 2006 Feb;61(2):157-65.

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