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Desoxyrhaponticin

Names

[ CAS No. ]:
30197-14-9

[ Name ]:
Desoxyrhaponticin

[Synonym ]:
Desoxyrhaponticin
3-hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl β-D-glucopyranoside
Deoxyrhapontin from rhubarb root
3,5-Dihydroxy-4 inverted exclamation marka-methoxystilbene 3-O-|A-D-glucoside
3-Hydroxy-5-[(E)-2-(4-methoxyphenyl)vinyl]phenyl β-D-glucopyranoside
Deoxyrhapontin
β-D-Glucopyranoside, 3-hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl

Biological Activity

[Description]:

Desoxyrhaponticin is a stilbene glycoside from the Tibetan nutritional food Rheum tanguticum Maxim. Desoxyrhaponticin is a Fatty acid synthase (FAS) inhibitor, and has apoptotic effect on human cancer cells[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Fatty Acid Synthase (FAS)

[References]

[1]. Li P, et al. Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan nutritional food Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
700.5±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H24O8

[ Molecular Weight ]:
404.410

[ Flash Point ]:
377.5±32.9 °C

[ Exact Mass ]:
404.147125

[ PSA ]:
128.84000

[ LogP ]:
1.48

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.691

[ Storage condition ]:
2-8°C

Safety Information

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route