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Reutericyclin

Names

[ CAS No. ]:
303957-69-9

[ Name ]:
Reutericyclin

[Synonym ]:
Reutericyclin
(2R)-4-acetyl-1,2-dihydro-5-hydroxy-2-(2-methylpropyl)-1-[(2E)-1-oxodec-2-enyl]-3H-pyrrol-3-one
(5R)-3-Acetyl-1-(2-decenoyl)-2-hydroxy-5-isobutyl-Δ2-pyrroline-4-one
(R)-4-Acetyl-1-((E)-dec-2-enoyl)-5-hydroxy-2-isobutyl-1,2-dihydro-pyrrol-3-one

Biological Activity

[Description]:

Reutericyclin (Reutericycline), a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri. Reutericyclin (Reutericycline) exhibits a broad inhibitory spectrum including Lactobacillus spp., Bacillus subtilis, B. cereus, Enterococcus faecalis, Staphylococcus aureus, and Listeria innocua[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Lin XB, et al. Genetic determinants of reutericyclin biosynthesis in Lactobacillus reuteri. Appl Environ Microbiol. 2015 Mar;81(6):2032-41.

[2]. Gänzle MG, et al. Characterization of reutericyclin produced by Lactobacillus reuteri LTH2584. Appl Environ Microbiol. 2000 Oct;66(10):4325-33.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H31NO4

[ Molecular Weight ]:
349.46400

[ Exact Mass ]:
349.22500

[ PSA ]:
74.68000

[ LogP ]:
4.02560

Related Compounds