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Alytesin TFA

Names

[ CAS No. ]:
31078-12-3

[ Name ]:
Alytesin TFA

[Synonym ]:
pGlu-Gly-Arg-Leu-Gly-Thr-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
pE-GRLGTQWAVGHLM-NH2
GLP-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2
PYR-GLY-ARG-LEU-GLY-THR-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2

Biological Activity

[Description]:

Alytesin, a bombesin-like peptide, is found in extracts of the skin of Alytes obstetricans. Alytesin reduces gastric acid secretion and induces hypertension. Alytesin also induces short-term anorexigenic effects in neonatal chicks[1][2][3]

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Guglietta A, et al. Central neuromodulation of gastric acid secretion by bombesin-like peptides. Peptides. 1985;6 Suppl 3:75-81.  

[2]. Erspamer V, et al. Some pharmacological actions of alytesin and bombesin. J Pharm Pharmacol. 1970 Nov;22(11):875-6.  

[3]. Cline MA, et al. Central and peripheral alytesin cause short-term anorexigenic effects in neonatal chicks. Neuropeptides. 2008 Jun;42(3):283-91.  

Chemical & Physical Properties

[ Molecular Formula ]:
C68H106N22O17S

[ Molecular Weight ]:
1535.77000

[ Exact Mass ]:
1534.78000

[ PSA ]:
645.48000

[ LogP ]:
2.06950

Safety Information

[ WGK Germany ]:
3

Related Compounds