Anti-MRSA agent 8

Names

[ CAS No. ]:
3118-36-3

[ Name ]:
Anti-MRSA agent 8

Biological Activity

[Description]:

Anti-MRSA agent 8 (Compound 7g) is a DAPG derivative with strong antibacterial activity. Anti-MRSA agent 8 assertes its activity by targeting bacterial cell membranes. Anti-MRSA agent 8 can be used for the research of methicillin-resistant Staphylococcus aureus (MRSA)[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Zhong Y, et al. 2,4-Diacetylphloroglucinol (DAPG) derivatives rapidly eradicate methicillin-resistant staphylococcus aureus without resistance development by disrupting membrane. Eur J Med Chem. 2023 Sep 29;261:115823.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H30O5

[ Molecular Weight ]:
350.44900

[ Exact Mass ]:
350.20900

[ PSA ]:
94.83000

[ LogP ]:
5.10960

Synthetic Route

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Precursor & DownStream

Precursor

DownStream