6-Me-ATP

Names

[ CAS No. ]:
3130-39-0

[ Name ]:
6-Me-ATP

[Synonym ]:
N6-methyl-O5'-(tetrahydroxy-[1]triphosphoryl)-adenosine
N6-Methyladenosin-5'-triphosphat
Methyl-N6-ATP
N6-methyl-ATP
6-Methylamino-9β-D-ribofuranosyl-purin-5'-triphosphat

Biological Activity

[Description]:

6-Me-ATP (N6-Methyl-ATP) is a N6-modified ATP derivative. 6-Me-ATP shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> GSK-3
Research Areas >> Others
Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3

[References]

[1]. Dong X, et al. Proteome-Wide Characterizations of N6-Methyl-Adenosine Triphosphate- and N6-Furfuryl-Adenosine Triphosphate-Binding Capabilities of Kinases. Anal Chem. 2021 Oct 5;93(39):13251-13259.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H18N5O13P3

[ Molecular Weight ]:
521.21

[ Exact Mass ]:
521.01100

[ PSA ]:
294.57000

Related Compounds