H-Phe-ol

Names

[ Name ]:
H-Phe-ol

[Synonym ]:
Ethanol, 2- (phenylamino)-
β-Anilinoethanol
HPH
(S)-(-)-2-amino-3-phenylpropan-1-ol
(S)-2-Amino-3-phenyl-1-propanol
(S)-2-Amino-3-phenylpropan-1-ol
(S)-2-amino-2-phenylpropan-1-ol
(S)-2-Amino-3-phenyl-propan-1-ol
N-(β-hydroxy)ethylaniline
Aniline, N-(β-hydroxyethyl)-
Ethanol, 2-(phenylamino)-
L(-)-2-Amino-3-phenyl-1-propanol
2-(phenylamino)ethanol
EINECS 221-674-4
H-Phenylalaninol
(S)-(-)-2-Amino-3-phenyl-1-propanol
(S)-(-)-phenylalaninol
(2S)-2-amino-3-phenylpropanol
(2S)-2-Amino-3-phenyl-1-propanol
(-)-L-PHENYLALANINOL
(2S)-2-amino-3-phenylpropan-1-ol
L-phenylalaninol
(S)-β-Aminobenzenepropanol
phenylalaninol
Benzenepropanol, β-amino-, (βS)-
2-amino-3-phenylpropan-1-ol
(S)-(−)-2-Amino-3-phenyl-1-propanol
N-(β-Hydroxyethyl)aniline
2-Amino-3-Phenyl-Propan-1-Ol
2-Anilinoethanol
H-Phe-ol
MFCD00004732
(±)-phenylethanolamine
N-2-hydroxyethylaniline
L-Phenylglycinol

Biological Activity

[Description]:

L-(-)-Phenylalaninol is an alanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1093.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
303.8±22.0 °C at 760 mmHg

[ Melting Point ]:
92-94ºC

[ Molecular Formula ]:
C₉H₁₃NO

[ Molecular Weight ]:
151.206

[ Flash Point ]:
137.5±22.3 °C

[ Exact Mass ]:
151.099716

[ PSA ]:
46.25000

[ LogP ]:
0.77

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.561

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA6900000

CHEMICAL NAME :: 1-Propanol, 2-amino-3-phenyl-, L-

CAS REGISTRY NUMBER :: 3182-95-4

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H13-N-O

MOLECULAR WEIGHT :: 151.23

WISWESSER LINE NOTATION :: Q1YZ1R -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,854,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 76 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,1578,1977

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
UN 3259 8/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
UA6900000

[ Hazard Class ]:
8.0

[ HS Code ]:
29221980

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Straightforward methodology for the enantioselective synthesis of benzo[a]- and indolo[2,3-a]quinolizidines.

J. Org. Chem. 72(14) , 5193-201, (2007)

An enantioselective two-step route to substituted benzo[a]- and indolo[2,3-a]quinolizidines has been developed. It consists of (i) a stereoselective cyclocondensation of a racemic or prochiral delta-o...

Direct high-performance liquid chromatographic separation of the enantiomers of an aromatic amine and four aminoalcohols using polysaccharide chiral stationary phases and acidic additive.

Chirality 19(8) , 647-53, (2007)

The HPLC enantiomeric separation of N-benzyl-alpha-methyl-benzylamine, phenylalaninol, tryptophanol, 2 (diphenylhydroxymethyl)pyrrolidine, and isoproterenol was accomplished in the normal-phase mode u...

Paracelsin; characterization by NMR spectroscopy and circular dichroism, and hemolytic properties of a peptaibol antibiotic from the cellulolytically active mold Trichoderma reesei. Part B.

Experientia 40 , 1189, (1984)

Paracelsin, a hemolytic and membrane active polypeptide antibiotic of the peptaibol class which is excreted by the mold Trichoderma reesei, was obtained by a simplified and rapid isolation procedure u...