2-Methyltetrahydrofuran-3-one

Names

[ Name ]:
2-Methyltetrahydrofuran-3-one

[Synonym ]:
3(2H)-Furanone, dihydro-2-methyl-
2-methyltetrahydro-3-furanone
2-methyl-4,5-dihydro-3-furanone
2-methyldihydrofuran-3(2H)-one
Tetrahydro-2-methylfuran-3-one
Dihydro-2-methyl-3-furanone
2-Methyltetrahydro-3-furanone (4,5-Dihydro-2-methyl-3(2H)-furanone
2-Methyltetrahydrofuran-3-One
2-Methyl-2H-furan-3-one
2-Methyldihydro-3(2H)-furanone
2-Methyl tetrahydrofuran-3-one
MFCD00010423
EINECS 221-685-4
2-Methyl-3-oxotetrahydrofuran
2-Methyl tetrahydro-3-furanone
4,5-Dihydro-2-methyl-3(2H)-furanone
UNII:I3703CL967

Biological Activity

[Description]:

2-Methyltetrahydrofuran-3-one is one of the volatile constituents of roasted coffee[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. A San Martin, et al. The isolation and structure determination of chilenone A, a putative dimer of 2-methyl-3(2H)-furanone from the marine alga Laurenciachilensis. Tetrahedron Letters 24(38):4063–4066.

Chemical & Physical Properties

[ Density]:
1.045

[ Boiling Point ]:
139 ºC

[ Molecular Formula ]:
C₅H₈O₂

[ Molecular Weight ]:
100.116

[ Flash Point ]:
38 ºC

[ Exact Mass ]:
100.052429

[ PSA ]:
26.30000

[ LogP ]:
-0.65

[ Vapour Pressure ]:
6.6±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.426-1.431

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU3579000

CHEMICAL NAME :: 3(2H)-Furanone, dihydro-2-methyl-

CAS REGISTRY NUMBER :: 3188-00-9

BEILSTEIN REFERENCE NO. :: 1341334

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C5-H8-O2

MOLECULAR WEIGHT :: 100.13

WISWESSER LINE NOTATION :: T5O CVTJ B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1860 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 3,249,1980

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H302

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S16-S26-S36/37/39-S24/25

[ RIDADR ]:
UN 1224 3/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
LU3579000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2932190090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Biofilm formation and acyl homoserine lactone production in Hafnia alvei isolated from raw milk.

Biol. Res. 42(4) , 427-36, (2009)

The objective of this study was to detect the presence of acyl homoserine lactones (AHLs), signal molecules of the quorum sensing system in biofilm formed by Hafnia alvei strains. It also evaluated th...