5-Iso-ZnAF-1

Names

[ Name ]:
5-Iso-ZnAF-1

[Synonym ]:
5-{2-[Bis(2-pyridylmethyl)amino]ethylamino}fluorescein
ZnAF-1

Biological Activity

[Description]:

ZnAF-1, a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn2+ detection . ZnAF-1 can bind Zn(II) with a 1 : 1 stoichiometry[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Anna Staszewska, et al. Ternary complex formation and competition quench fluorescence of ZnAF family zinc sensors. Metallomics

Chemical & Physical Properties

[ Density]:
1.443g/cm3

[ Boiling Point ]:
844.065ºC at 760 mmHg

[ Molecular Formula ]:
C₃₄H₂₈N₄O₅

[ Molecular Weight ]:
572.61000

[ Flash Point ]:
464.274ºC

[ Exact Mass ]:
572.20600

[ PSA ]:
128.79000

[ LogP ]:
5.94590

[ Index of Refraction ]:
1.737

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Improvement and biological applications of fluorescent probes for zinc, ZnAFs.

J. Am. Chem. Soc. 124 , 6555-6562, (2002)

The development and cellular applications of novel fluorescent probes for Zn2+, ZnAF-1F, and ZnAF-2F are described. Fluorescein is used as a fluorophore of ZnAFs, because its excitation and emission w...

Hirano, T., et al.

J. Am. Chem. Soc. 122 , 12399-12400 , (2000)