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des-o-methyllasiodiplodin

Names

[ CAS No. ]:
32885-82-8

[ Name ]:
des-o-methyllasiodiplodin

[Synonym ]:
1H-2-Benzoxacyclododecin-1-one, 3,4,5,6,7,8,9,10-octahydro-12,14-dihydroxy-3-methyl-, (3S)-
(3S)-12,14-Dihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclododecin-1-one

Biological Activity

[Description]:

De-O-Methyllasiodiplodin, a cytotoxic compound, can be isolated from Ludwigia hyssopifolia. De-O-Methyllasiodiplodin inhibits Hep-2 cell growth by inducing apoptosis[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. hang J, et al. Cytotoxic Compounds From Ludwigia hyssopifolia. Natural Product Communications. 2019;14(9).

[2]. Peng Y, et al. de-O-methyllasiodiplodin from Ludwigia hyssop folia causes death of human liver cancer cells through the mitochondrial apoptotic, Akt/NF-κB and STAT3 pathway in vitro. The Journal of Phytopharmacology. 2022. 11(4).

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
509.8±29.0 °C at 760 mmHg

[ Melting Point ]:
120-125℃ (hexane )

[ Molecular Formula ]:
C16H22O4

[ Molecular Weight ]:
278.34

[ Flash Point ]:
189.0±17.8 °C

[ Exact Mass ]:
278.151794

[ LogP ]:
4.78

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.530

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds