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Quetiapine sulfoxide (dihydrochloride)

Names

[ CAS No. ]:
329218-11-3

[ Name ]:
Quetiapine sulfoxide (dihydrochloride)

[Synonym ]:
Ethanol,2-[2-[4-(5-oxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]-,dihydrochloride
Quetiapine sulfoxide (dihydrochloride)
2-[2-[4-(5-Oxidodibenzo[b,f][1,4]Thiazepin-11-Yl)-1-Piperazinyl]Ethoxy]-Ethanol ,Dihydrochloride

Biological Activity

[Description]:

Quetiapine Sulfoxide is a metabolite of Quetiapine. Quetiapine is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder, and along with an antidepressant to treat major depressive disorder.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor
Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor
Research Areas >> Neurological Disease

[References]

[1]. Denys D, et al. Quetiapine addition to serotonin reuptake inhibitor treatment in patients with treatment-refractory obsessive-compulsive disorder: an open-label study. J Clin Psychiatry. 2002 Aug;63(8):700-703.


[Related Small Molecules]

Harmine | CB-154 mesylate | Pimavanserin | SCH 23390 hydrochloride | Levodopa | Cabergoline | Serotonin hydrochloride | Sodium Ferulate | Thioridazine hydrochloride | Brexpiprazole | Domperidone | Trifluoperazine dihydrochloride | pimozide | Risperidone | SKF38393 HCl

Chemical & Physical Properties

[ Molecular Formula ]:
C21H27Cl2N3O3S

[ Molecular Weight ]:
472.42800

[ Exact Mass ]:
471.11500

[ PSA ]:
84.58000

[ LogP ]:
3.65260

[ Storage condition ]:
2-8℃

Related Compounds