Boc-His(Trt)-OH

Names

[ Name ]:
Boc-His(Trt)-OH

[Synonym ]:
BOC-L-HIS(TRT)-OH
BOC-HIS(TRT)-OH
(S)-2-((tert-Butoxycarbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanoic acid
MFCD00153307
N-(tert-Butoxycarbonyl)-1-trityl-L-histidine
His(Trt)-OH
N-T-BUTOXYCARBONYL-N-TAU-TRITYL-L-HISTIDINE
N-Boc-His(Trt)-OH
L-Histidine, N-[(1,1-dimethylethoxy)carbonyl]-1-(triphenylmethyl)-
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-trityl-L-histidine
Boc-His(trt)
BOC-N-IM-TRITYL-L-HISTIDINE

Biological Activity

[Description]:

Boc-His(Trt)-OH is a histidine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
667.5±55.0 °C at 760 mmHg

[ Melting Point ]:
~130 °C (dec.)

[ Molecular Formula ]:
C₃₀H₃₁N₃O₄

[ Molecular Weight ]:
497.585

[ Flash Point ]:
357.5±31.5 °C

[ Exact Mass ]:
497.231445

[ PSA ]:
93.45000

[ LogP ]:
5.59

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.594

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Solid-phase synthesis of C-terminal azapeptides.

J. Pept. Sci. 21 , 387-91, (2015)

The solid-phase synthesis of azapeptides possessing a C-terminal aza-residue has been accomplished by a protocol featuring regioselective alkylation of benzhydrylidene-aza-glycinamide and illustrated ...