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Tau Peptide (275-305) (Repeat 2 domain)

Names

[ CAS No. ]:
330456-25-2

[ Name ]:
Tau Peptide (275-305) (Repeat 2 domain)

[Synonym ]:
L-Serine, L-valyl-L-glutaminyl-L-isoleucyl-L-isoleucyl-L-asparaginyl-L-lysyl-L-lysyl-L-leucyl-L-α-aspartyl-L-leucyl-L-seryl-L-asparaginyl-L-valyl-L-glutaminyl-L-seryl-L-lysyl-L-cysteinylglycyl-L-s eryl-L-lysyl-L-α-aspartyl-L-asparaginyl-L-isoleucyl-L-lysyl-L-histidyl-L-valyl-L-prolylglycylglycylglycyl-
L-Valyl-L-glutaminyl-L-isoleucyl-L-isoleucyl-L-asparaginyl-L-lysyl-L-lysyl-L-leucyl-L-α-aspartyl-L-leucyl-L-seryl-L-asparaginyl-L-valyl-L-glutaminyl-L-seryl-L-lysyl-L-cysteinylglycyl-L-seryl-L-lys yl-L-α-aspartyl-L-asparaginyl-L-isoleucyl-L-lysyl-L-histidyl-L-valyl-L-prolylglycylglycylglycyl-L-serine

Biological Activity

[Description]:

Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Dan-Jing Yang, et al. Mercury(II) promotes the in vitro aggregation of tau fragment corresponding to the second repeat of microtubule-binding domain: Coordination and conformational transition. Biopolymers. 2010 Dec;93(12):1100-7.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
2937.0±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C139H239N43O45S

[ Molecular Weight ]:
3264.711

[ Flash Point ]:
1730.0±34.3 °C

[ Exact Mass ]:
3262.745605

[ LogP ]:
-7.54

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.566

Related Compounds