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BAD (103-127) (human)

Names

[ CAS No. ]:
331762-68-6

[ Name ]:
BAD (103-127) (human)

Biological Activity

[Description]:

BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL. BAD (103-127) (human), the 25-mer Bad peptide, is reported to have almost 800-fold higher affinity for Bcl-XL than the 16-mer peptide[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family
Research Areas >> Cancer

[References]

[1]. Dilraj Lama, et al. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L). J Comput Aided Mol Des. 2011 May;25(5):413-26.

Chemical & Physical Properties

[ Molecular Formula ]:
C137H212N42O39S

[ Molecular Weight ]:
3103.47

Related Compounds