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5-HT7 agonist 1

Names

[ CAS No. ]:
334974-31-1

[ Name ]:
5-HT7 agonist 1

[Synonym ]:
1h-indole, 4-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-

Biological Activity

[Description]:

5-HT7 agonist 1 is a selective 5-HT7 receptor agonist, with an IC50 of 222.93 nM, can be used for the 5-HT7 receptor related disease, such as CNS disorders.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Research Areas >> Neurological Disease

[Target]

IC50: 222.93 nM (5-HT7 receptor)[1]


[In Vitro]

5-HT7 agonist 1 (Compound 33) is a selective 5-HT7 receptor agonist, with an IC50 of 222.93 nM, can be used for the 5-HT7 receptor related disease, such as CNS disorders[1].

[References]

[1]. Pascual-ramon, et al. 5HT7 RECEPTOR LIGANDS AND COMPOSITIONS COMPRISING THE SAME. 20110183991 A1.


[Related Small Molecules]

Harmine | Pimavanserin | Serotonin hydrochloride | Sodium Ferulate | Thioridazine hydrochloride | Brexpiprazole | Risperidone | TG6-10-1 | Cariprazine | Quetiapine | SERTINDOLE | Alprenolol hydrochloride | B-HT 920 | Ketanserin | Palonosetron hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C19H20ClN3

[ Molecular Weight ]:
325.83500

[ Exact Mass ]:
325.13500

[ PSA ]:
22.27000

[ LogP ]:
4.14640

Related Compounds