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6'-Iodoresiniferatoxin

Names

[ CAS No. ]:
335151-55-8

[ Name ]:
6'-Iodoresiniferatoxin

[Synonym ]:
[(1R,2R,6R,10S,11R,15R,17R)-13-Benzyl-6-hydroxy-15-isopropenyl-4,17-dimethyl-5-oxo-12,14,18-trioxapentacyclo[11.4.1.01,10.02,6.011,15]octadeca-3,8-dien-8-yl]methyl (4-hydroxy-2-iodo-5-methoxyphe nyl)acetate
Benzeneacetic acid, 4-hydroxy-2-iodo-5-methoxy-, [(3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[4',5':5,6]benzo[1,2-d]-1,3-dioxol-5-yl]methyl ester

Biological Activity

[Description]:

6'-Iodoresiniferatoxin (6'-IRTX) is a TRPV1 agonist used in the study of neuropathic pain[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel
Research Areas >> Neurological Disease

[References]

[1]. Jiang YL, et al. Low Frequency Electroacupuncture Alleviated Spinal Nerve Ligation Induced Mechanical Allodynia by Inhibiting TRPV1 Upregulation in Ipsilateral Undamaged Dorsal Root Ganglia in Rats. Evid Based Complement Alternat Med. 2013;2013:170910.  

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
813.0±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C37H39IO9

[ Molecular Weight ]:
754.60

[ Flash Point ]:
445.5±34.3 °C

[ Exact Mass ]:
754.163879

[ LogP ]:
7.37

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.671

Related Compounds