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Pangelin

Names

[ CAS No. ]:
33783-80-1

[ Name ]:
Pangelin

[Synonym ]:
hms2198i04
Pangelin

Biological Activity

[Description]:

Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities[1][2].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Pangelin shows a potent cytotoxic activity with the IC50s of 8.6 to 14.6 μg/mL against four kinds of tumor cell lines[1].

[References]

[1]. Thanh PN, et, al. Cytotoxic coumarins from the root of Angelica dahurica. Arch Pharm Res. 2004 Dec;27(12):1211-5.

[2]. Stavr M, et, al. Pangelin, an antimycobacterial coumarin from Ducrosia anethifolia. Planta Med. 2003 Oct;69(10):956-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H14O5

[ Molecular Weight ]:
286.27900

[ Exact Mass ]:
286.08400

[ PSA ]:
72.81000

[ LogP ]:
2.85500

Safety Information

[ Hazard Codes ]:
Xi