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Rovelizumab

Names

[ CAS No. ]:
339086-79-2

[ Name ]:
Rovelizumab

Biological Activity

[Description]:

Rovelizumab is a humanized monoclonal leukointegrin antibody. Rovelizumab is a monoclonal antibody directed against the CD11/CD18 cell adhesion proteins. Rovelizumab can be used for research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI) and stroke[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Cytoskeleton >> Integrin

[In Vitro]

Rovelizumab 结合 CD18 并对 CD18 整合素复合物具有活性，包括 CD11b-CD18 异源二聚体[2]。

[References]

[1]. Jones R. Rovelizumab (ICOS Corp). IDrugs. 2000 Apr;3(4):442-6.  

[2]. Qualls JE, et al. A double agent in cancer: stopping macrophages wounds tumors. Nat Med. 2010 Aug;16(8):863-4.  

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds