7-(4-Methoxybenzylamino)-4-nitrobenzoxadiazole

Names

[ Name ]:
7-(4-Methoxybenzylamino)-4-nitrobenzoxadiazole

[Synonym ]:
Benzofurazan,4-((p-methoxybenzyl)amino)-7-nitro
4-(4-Methoxybenzylamino)-7-nitrobenzofurazan
t56 bnonj fnw im1r do1[wln]
s-benzofurazanamine,N-[(4-methoxyphenyl)methyl]-7-nitro
4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole
7-(p-Methoxybenzylamino)-4-nitrobenz-2-oxa-1,3-diazol
4-(4-methoxybenzylamino)-7-nitrobenzofurazane
MFCD00042778
4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole,MBD
EINECS 251-775-9
MBD

Biological Activity

[Description]:

MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kenner RA, et al. A new fluorescent probe for protein and nucleoprotein conformation. Binding of 7-(p-methoxybenzylamino)-4-nitrobenzoxadiazole to bovine trypsinogen and bacterial ribosomes. Biochemistry. 1971;10(24):4433-4440.

[2]. Kasahara Y, et al. Formation of a conformationally changed C1r, a subcomponent of the first component of human complement, as an intermediate of its autoactivation reaction. FEBS Lett. 1982;141(1):128-131.

Chemical & Physical Properties

[ Density]:
1.438 g/cm3

[ Boiling Point ]:
500.8ºC at 760 mmHg

[ Melting Point ]:
178-182ºC

[ Molecular Formula ]:
C₁₄H₁₂N₄O₄

[ Molecular Weight ]:
300.26900

[ Flash Point ]:
256.7ºC

[ Exact Mass ]:
300.08600

[ PSA ]:
106.00000

[ LogP ]:
3.34790

[ Index of Refraction ]:
1.691

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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