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Trachelogenin

Names

[ CAS No. ]:
34209-69-3

[ Name ]:
Trachelogenin

[Synonym ]:
Trachelogenin
(-)-Trachelogenin

Biological Activity

[Description]:

Trachelogenin ((-)-Trachelogenin) is an HCV entry inhibitor without genotype specificity, and with low cytotoxicity. Trachelogenin inhibits HCVcc infection and HCVpp cell entry in a dose-dependent manner with an IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively. Trachelogenin exhibits effective antiviral, anti-inflammatory and analgesic effects[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HCV
Research Areas >> Infection
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[References]

[1]. Xi-Jing Qian, et al. Trachelogenin, a novel inhibitor of hepatitis C virus entry through CD81. J Gen Virol. 2016 May;97(5):1134-1144.

Chemical & Physical Properties

[ Density]:
1.300±0.06 g/cm3

[ Melting Point ]:
144 ºC

[ Molecular Formula ]:
C21H24O7

[ Molecular Weight ]:
388.41100

[ Exact Mass ]:
388.15200

[ PSA ]:
94.45000

[ LogP ]:
2.10730

[ Water Solubility ]:
Very slightly soluble (0.37 g/L) (25 ºC)

Related Compounds