<Suppliers Price>

Acetyl Podocarpic Acid Anhydride

Names

[ CAS No. ]:
344327-48-6

[ Name ]:
Acetyl Podocarpic Acid Anhydride

[Synonym ]:
(1S,4aS,10aR)-6-Acetoxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-1-phenanthrenecarboxylic anhydride

Biological Activity

[Description]:

Acetyl podocarpic acid anhydride is a potent, semisynthetic liver X receptor(LXR) agonist derived from extracts of the mayapple. Acetyl podocarpic acid anhydride has the potential to be useful for the prevention and treatment of atherosclerosis, especially in the context of low HDL levels[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> LXR

[References]

[1]. Sparrow CP, et al. A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux. J Biol Chem. 2002 Mar 22;277(12):10021-7.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
695.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C38H46O7

[ Molecular Weight ]:
614.768

[ Flash Point ]:
284.6±31.5 °C

[ Exact Mass ]:
614.324341

[ PSA ]:
95.97000

[ LogP ]:
8.78

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.557

Related Compounds