Azido-PEG5-azide

Names

[ Name ]:
Azido-PEG5-azide

[Synonym ]:
bisazido hexaethylene glycol
3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-azide
Azido-PEG5-Azide
1,17-DIAZIDO-3,6,9,12,15-PENTAOXAHEPTADECANE

Biological Activity

[Description]:

Azido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₂₄N₆O₅

[ Molecular Weight ]:
332.35600

[ Exact Mass ]:
332.18100

[ PSA ]:
145.65000

[ LogP ]:
0.59552

Azido-PEG5-azide

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds