Ani9

Names

[ Name ]:
Ani9

[Synonym ]:
Acetic acid, 2-(4-chloro-2-methylphenoxy)-, 2-[(1E)-(2-methoxyphenyl)methylene]hydrazide
Ani 9
MFCD00635759
2-(4-Chloro-2-methylphenoxy)-N'-[(E)-(2-methoxyphenyl)methylene]acetohydrazide

Biological Activity

[Description]:

Ani9 is a potent and selective transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with an IC50 of 77 nM[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Chloride Channel

Research Areas >> Others

[References]

[1]. Seo Y, et al. Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2. PLoS One. 2016 May 24;11(5):e0155771.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C₁₇H₁₇ClN₂O₃

[ Molecular Weight ]:
332.781

[ Exact Mass ]:
332.092773

[ LogP ]:
4.47

[ Index of Refraction ]:
1.563

[ Storage condition ]:
-20°C

Ani9

Names

Biological Activity

Chemical & Physical Properties

Related Compounds