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[1S,6S,(+)]-6-Methyl-3-(1-methylethylidene)-7-oxabicyclo[4.1.0]heptane-2-one

Names

[ CAS No. ]:
3564-96-3

[ Name ]:
[1S,6S,(+)]-6-Methyl-3-(1-methylethylidene)-7-oxabicyclo[4.1.0]heptane-2-one

[Synonym ]:
rotundifolone
(1S,6S)-3-Isopropylidene-6-methyl-7-oxa-bicyclo[4.1.0]heptan-2-one
(1S)-1,2-Epoxy-p-menth-4(8)-en-3-on
(+)-piperitenone oxide
(1S,2S)-piperitenone oxide
(1S)-1,2-epoxy-p-menth-4(8)-en-3-one
Piperitenone oxide

Biological Activity

[Description]:

Piperitenone oxide (lippione), a monoterpene, can be isolated from the n-hexane extract from spearmint (Mentha spicata) leaves. Piperitenone oxide is a potent inducer of differentiation in a RCM-1 human colon cancer cell line[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Nakamura Y, et al. Differentiation-inducing effect of piperitenone oxide, a fragrant ingredient of spearmint (Mentha spicata), but not carvone and menthol, against human colon cancer cells[J]. journal of functional foods, 2014, 8: 62-67.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H14O2

[ Molecular Weight ]:
166.21700

[ Exact Mass ]:
166.09900

[ PSA ]:
29.60000

[ LogP ]:
1.84320

Related Compounds