Phenylethynylcarbinol carbamate

Names

[ CAS No. ]:
3567-38-2

[ Name ]:
Phenylethynylcarbinol carbamate

[Synonym ]:
Phenylethynylcarbinol carbamate
Carfimat
1-Phenyl-2-propynyl carbamate
Nirvotin
Carfimate

Biological Activity

[Description]:

Phenylethynylcarbinol carbamate is a hypnotic agent[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. GHISONI T. A proposito di un nuovo ipnotico, carbammato di fenil-etinil-carbinolo [A new hypnotic drug, phenylethynylcarbinol carbamate]. Gazz Med Ital. 1956;115(8):242-247.

Chemical & Physical Properties

[ Density]:
1.192g/cm3

[ Boiling Point ]:
320.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₉NO₂

[ Molecular Weight ]:
175.18400

[ Flash Point ]:
165.2ºC

[ Exact Mass ]:
175.06300

[ PSA ]:
53.31000

[ LogP ]:
1.97000

[ Index of Refraction ]:
1.569

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DO5950000

CHEMICAL NAME :: Benzyl alcohol, alpha-ethynyl-, carbamate

CAS REGISTRY NUMBER :: 3567-38-2

BEILSTEIN REFERENCE NO. :: 3200625

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H9-N-O2

MOLECULAR WEIGHT :: 175.20

WISWESSER LINE NOTATION :: ZVOYR&1UU1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 99,245,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 99,245,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 6,136,1956

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%