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15-oxoprostaglandin F2α

Names

[ CAS No. ]:
35850-13-6

[ Name ]:
15-oxoprostaglandin F2α

[Synonym ]:
15-oxoprostaglandin F2α
15-oxo-prostaglandin F2α
15-oxo-prostaglandin F2alpha
(5Z,9α,11α,13E)-9,11-Dihydroxy-15-oxoprosta-5,13-dien-1-oic acid
Prosta-5,13-dien-1-oic acid, 9,11-dihydroxy-15-oxo-, (5Z,9α,11α,13E)-
15-ketoprostaglandin F2A
15-Ketoprostaglandinef2alpha
9ALPHA,11ALPHA-DIHYDROXY-15-OXO-PROSTA-5Z,13E-DIEN-1-OIC ACID
15-KETO PROSTAGLANDIN F2ALPHA
15-Keto PGF2a

Biological Activity

[Description]:

15-keto-Prostaglandin F2α (15-keto-PGF2α) is a metabolite of Prostaglandin F2α. Prostaglandin F2α. Prostaglandin F2α is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist and plays a key role in the onset and progression of labour[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[Target]

Human Endogenous Metabolite


[References]

[1]. S Basu. Radioimmunoassay of 15-keto-13,14-dihydro-prostaglandin F2alpha: an index for inflammation via cyclooxygenase catalysed lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids. 1998 May;58(5):347-52.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
535.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H32O5

[ Molecular Weight ]:
352.465

[ Flash Point ]:
291.5±26.6 °C

[ Exact Mass ]:
352.224976

[ PSA ]:
94.83000

[ LogP ]:
1.84

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.561

[ Storage condition ]:
-20°C

Related Compounds