<Suppliers Price>

N-ACETYLNEURAMIN-LACTOSE

Names

[ CAS No. ]:
35890-39-2

[ Name ]:
N-ACETYLNEURAMIN-LACTOSE

[Synonym ]:
6'-Sialyllactose (6'-SL)
6'-Sialyllactose
6'-Monosialyllactose
6’-Sialyllactose
6'-a-Sialyllactose

Biological Activity

[Description]:

6'-Sialyllactose is a sialylated human milk oligosaccharide that can promote the proliferation of bifidobacteria and shaping the gut microbiota. 6'-Sialyllactose also inhibits toll-like receptor 4 signaling and protects against the development of necrotizing enterocolitis[1][2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)
Research Areas >> Inflammation/Immunology

[In Vitro]

6'-Sialyllactose (10 mg/mL; 补充婴儿配方奶粉) 以剂量依赖性方式预防小鼠坏死性小肠结肠炎 (NEC)[1]。

[References]

[1]. Sodhi CP, et, al. The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling. Pediatr Res. 2021 Jan;89(1):91-101.  

[2]. Zhu Y, et, al. Recent progress on health effects and biosynthesis of two key sialylated human milk oligosaccharides, 3'-sialyllactose and 6'-sialyllactose. Biotechnol Adv. 2023 Jan-Feb;62:108058.  

Chemical & Physical Properties

[ Density]:
1.72 g/cm3

[ Boiling Point ]:
1134.9ºC at 760 mmHg

[ Molecular Formula ]:
C23H39NO19

[ Molecular Weight ]:
633.55

[ Flash Point ]:
640.1ºC

[ Exact Mass ]:
633.21200

[ PSA ]:
342.92000

Safety Information

[ Hazard Codes ]:
Xi

[ WGK Germany ]:
3

Related Compounds