Mal-C2-cyclohexylcarboxyl-hydrazide TFA
Names
[ CAS No. ]:
359436-59-2
[ Name ]:
Mal-C2-cyclohexylcarboxyl-hydrazide TFA
[Synonym ]:
MFCD01863409
4-[(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexanecarbohydrazide trifluoroacetate (1:1)
Biological Activity
[Description]:
Mal-C2-cyclohexylcarboxyl-hydrazide (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
Alkyl-Chain
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C14H18F3N3O5
[ Molecular Weight ]:
365.305
[ Exact Mass ]:
365.119843