4-Biphenylylmethanol
Names
[ CAS No. ]:
3597-91-9
[ Name ]:
4-Biphenylylmethanol
[Synonym ]:
MFCD00004660
4-Biphenylmethanol
4-HydroxyMethylbiphenyl
4-Hydroxymethyl-biphenyl
(4-phenylphenyl)methanol
[1,1'-Biphenyl]-4-methanol
Biphenyl-4-methanol
4-Biphenylylmethanol
4-Phenylbenzyl Alcohol
biphenyl-4-ylmethanol
[1,1'-Biphenyl]-4-ylmethanol
EINECS 222-745-2
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
340.0±21.0 °C at 760 mmHg
[ Melting Point ]:
96-100 °C(lit.)
[ Molecular Formula ]:
C13H12O
[ Molecular Weight ]:
184.234
[ Flash Point ]:
154.9±17.8 °C
[ Exact Mass ]:
184.088821
[ PSA ]:
20.23000
[ LogP ]:
2.79
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.595
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV5425000
- CHEMICAL NAME :
- 4-Biphenylmethanol
- CAS REGISTRY NUMBER :
- 3597-91-9
- BEILSTEIN REFERENCE NO. :
- 1937761
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C13-H12-O
- MOLECULAR WEIGHT :
- 184.25
- WISWESSER LINE NOTATION :
- Q1R DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 7-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - body wall
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 39,537,1989
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 500 mg/kg
- SEX/DURATION :
- male 5 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 100,345,1982
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1250 mg/kg
- SEX/DURATION :
- male 5 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 100,345,1982
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DV5425000
[ HS Code ]:
29062900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2906299090
[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
Mutat. Res. 100(1-4) , 207-9, (1982)
An assay for mutagenic activity of 4CMB, 4HMB and BC, using the "microtitre" fluctuation test.
Mutat. Res. 100(1-4) , 81-5, (1982)
4CMB, 4HMB and BC were assayed for mutagenic activity using the 'microtitre' bacterial fluctuation test without metabolic activation. 4CMB was positive in strains of Salmonella typhimurium detecting b...
Mutation at the TK locus of mouse lymphoma L5178Y cells by 4CMB, 4HMB and BC.Mutat. Res. 100(1-4) , 249-51, (1982)