Ibuprofen Alcohol

Names

[ Name ]:
Ibuprofen Alcohol

[Synonym ]:
2-[4-(2-methylpropyl)phenyl]propan-1-ol
2-(4-Isobutylphenyl)-1-propanol
UNII:074734J69N
Benzeneethanol, β-methyl-4-(2-methylpropyl)-
Ibuprofen Impurity 16

Biological Activity

[Description]:

Ibuprofen alcohol, a nonsteroidal antiinflammatory drug (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Timothy Lynagh, et al. Molecular Basis for Allosteric Inhibition of Acid-Sensing Ion Channel 1a by Ibuprofen. J Med Chem. 2017 Oct 12;60(19):8192-8200.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
223.9±8.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₂₀O

[ Molecular Weight ]:
192.297

[ Flash Point ]:
105.3±3.7 °C

[ Exact Mass ]:
192.151413

[ PSA ]:
20.23000

[ LogP ]:
3.58

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.510

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2906299090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2906299090

[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%