PIK-inhibitors

Names

[ CAS No. ]:
371934-59-7

[ Name ]:
PIK-inhibitors

[Synonym ]:
Benzenamine, 3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]-
MFCD30475673
3-[4-(4-Morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]aniline

Biological Activity

[Description]:

PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC50 of 6.85[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PI3K/Akt/mTOR >> PI3K

[References]

[1]. Li Y, et al. Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110alpha inhibitors. J Mol Model. 2010 Sep;16(9):1449-60.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
526.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₇N₅O₂

[ Molecular Weight ]:
347.371

[ Flash Point ]:
272.0±30.1 °C

[ Exact Mass ]:
347.138214

[ LogP ]:
0.80

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.720

[ Storage condition ]:
-20℃

PIK-inhibitors

Names

Biological Activity

Chemical & Physical Properties

Related Compounds