Human β-defensin-2

Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus[1]. Human β-defensin-2 can be used for the study of colitis[2].

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

Target: bacteria[1]

[1]. J M Schröder, et al. Human beta-defensin-2. Int J Biochem Cell Biol

[2]. Louis Koeninger, et al. Human β-Defensin 2 Mediated Immune Modulation as Treatment for Experimental Colitis. Front Immunol. 2020 Jan 31;11:93.