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Jacareubin

Names

[ CAS No. ]:
3811-29-8

[ Name ]:
Jacareubin

[Synonym ]:
xanthone V1
5,9,10-Trihydroxy-2,2-dimethyl-2H-pyrano[3,2-b]xanthen-6-on
Jacareubin
sulfasalazine
5,9,10-trihydroxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one
2H,6H-Pyrano[3,2-b]xanthen-6-one,5,9,10-trihydroxy-2,2-dimethyl
5,9,10-trihydroxy-2,2-dimethyl-2H-pyrano[3,2-b]xanthen-6-one

Biological Activity

[Description]:

Jacareubin is a xanthone compound that can be isolated from Calophyllum brasiliense. Jacareubin has antibacterial, antioxidant, gastroprotective properties, and also has certain cancer cell toxicity, which can be used in cancer research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. W R García-Niño, et al. Cytogenetic effects of Jacareubin from Calophyllum brasiliense on human peripheral blood mononucleated cells in vitro and on mouse polychromatic erythrocytes in vivo. Toxicol Appl Pharmacol. 2017 Nov 15;335:6-15.   

Chemical & Physical Properties

[ Density]:
1.493g/cm3

[ Boiling Point ]:
553.1ºC at 760 mmHg

[ Molecular Formula ]:
C18H14O6

[ Molecular Weight ]:
326.30

[ Flash Point ]:
206.5ºC

[ Exact Mass ]:
326.07900

[ PSA ]:
100.13000

[ LogP ]:
3.24720

[ Index of Refraction ]:
1.693

Precursor & DownStream

Precursor

DownStream

Related Compounds